Briefly, samples containing more than 0.5 g/ml D dimer produce a blue colour in the presence of nitroblue tetrazolium, the intensity of which reflects the concentration of D dimer. D dimer results were scored as normal (no colour development), abnormal, or inadequate for interpretation. Assuming an expected prevalence of 30% for deep vein thrombosis we calculated that about 900 patients would be necessary to yield sufficiently narrow confidence intervals around the expected number of venous thromboembolic complications..
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